Infectious diseases remain one of the major causes of death world-wide. Emerging infections, such as the current COVID-19 pandemic, but also the dramatic increase in antibiotic resistance illustrate the urgent need for novel antimicrobial interventions.
Vaccines represent one of the most powerfull, safe and cost-effective tools to fight infectious diseases. However, efficient vaccines against many serious infections including many causes of pneumonia and hospital acquired infections are still missing.
We aim to decipher host & pathogen interactions in humans and to understand the mechanisms that determine protective immunity elicited by infections and vaccines. We are particularly interested in the earliest events of the immune response and how they shape protective immunity.
Currently, we focus much of our efforts on dissecting human immune responses to SARS-CoV-2 and how they impact severity of COVID-19 and the generation of protective immunity.
If you are interested in our work or in joining the team please contact us.